Key result
In patients with clear cell RCC, chemical-shift MRI differentiated adrenal adenomas from metastases, with a mean signal intensity index of 45.0% for adenomas versus 6.6% for metastases (P<0.001).
Why the study?
Can chemical-shift MRI and MR feature analysis differentiate adrenal adenomas from metastases in patients with clear cell renal cell carcinoma?
Population
24 patients with clear cell renal cell carcinoma undergoing MR for evaluation of an adrenal mass
Design
Cross-sectional
Authors
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May aid differentiation of adrenal lesions in clear cell RCC; leaves open prospective validation before adoption.
Observational (n=24)
Can chemical-shift MRI and MR feature analysis differentiate adrenal adenomas from metastases in patients with clear cell renal cell carcinoma?
Absolute Event Rate: 45% vs 6.6%
p-value: p=<0.001
Chemical-shift MRI and specific MR features such as cystic change, necrosis, and hemorrhage can effectively differentiate adrenal adenomas from metastases in patients with clear cell renal cell carcinoma.
Woo et al. (2013) conducted an observational in Adrenal mass in patients with clear cell renal cell carcinoma (n=24). Adrenal adenoma vs. Adrenal metastasis was evaluated on Mean signal intensity index (SII) (p=<0.001). In patients with clear cell RCC, chemical-shift MRI differentiated adrenal adenomas from metastases, with a mean signal intensity index of 45.0% for adenomas versus 6.6% for metastases (P<0.001).
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