Why the study?
Does procalcitonin provide better information about the severity and course of multiple organ dysfunction syndrome compared to C-reactive protein?
Population
40 patients with systemic inflammation and consecutive multiple organ dysfunction syndrome (MODS)
Design
Cohort
Follow-up
15 days
Authors
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May inform MODS severity assessment more than CRP; leaves open whether PCT monitoring improves outcomes in critical care.
Does procalcitonin provide better information about the severity and course of multiple organ dysfunction syndrome compared to C-reactive protein?
Procalcitonin correlates better with the severity of multiple organ dysfunction syndrome (as measured by SOFA score) and mortality than C-reactive protein.
Meisner et al. (1999) studied this question.
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