Why the study?
Does bilateral stellate ganglionectomy alter basal cardiovascular function and responses to atenolol in rats?
Population
Rats (n=17)
Comparison
Bilateral stellate ganglionectomy followed by 5… vs Sham surgery followed by 5 days of atenolol…
Design
Preclinical
Follow-up
23 days
Authors
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Limits cardiac sympathetic role in rat basal hemodynamics; leaves open translation to human autonomic regulation.
Does bilateral stellate ganglionectomy alter basal cardiovascular function and responses to atenolol in rats?
Cardiac sympathetic nerves appear relatively unimportant in maintaining basal mean arterial pressure or the depressor response to atenolol in conscious rats.
Yoshimoto et al. (2008) studied this question.
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