Why the study?
Does bilateral cardiac sympathetic denervation reduce VT/VF inducibility and improve electrical stability in infarcted pig hearts?
Population
6 normal and 18 infarcted pigs
Comparison
Bilateral cardiac sympathetic denervation vs Baseline (before CSD)
Design
Preclinical
Authors
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Bilateral CSD may stabilize post-MI electrical properties without hemodynamic cost; leaves open human translation and long-term efficacy.
Does bilateral cardiac sympathetic denervation reduce VT/VF inducibility and improve electrical stability in infarcted pig hearts?
Bilateral cardiac sympathetic denervation reduces VT/VF inducibility and improves electrical stability in infarcted hearts while maintaining hemodynamic stability via the middle cervical ganglion.
Irie et al. (2016) studied this question.
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