Why the study?
Which antihypertensive agents provide the most satisfactory control of blood pressure and heart rate during the morning hours?
Population
Patients in ambulatory blood pressure studies
Comparison
Antihypertensive agents vs Other forms of drug therapy
Design
Review
Authors
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May support preferential morning BP control with these agents; leaves open confirmation of CV outcome benefit in prospective trials.
Which antihypertensive agents provide the most satisfactory control of blood pressure and heart rate during the morning hours?
Labetalol, nifedipine, and verapamil are particularly effective at blunting the morning surge in blood pressure, which may be relevant for preventing morning cardiovascular events.
Mark A. Sirgo (1988) studied this question.
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