April 1, 2001Blood Pressure Monitoring
Cardiovascular risk and therapeutic intervention for the early morning surge in blood pressure and heart rate
Why the study?
Do chronotherapeutic formulations and long-acting antihypertensive agents improve 24-hour blood pressure control and attenuate the early morning blood pressure surge in hypertensive patients?
Population
Hypertensive patients and susceptible individuals at risk for cardiovascular events
Design
Review
Authors
Discussion
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Member takes
Implication
Supports chronotherapy for morning BP control; leaves open dedicated outcome trials before practice change.
Structured PICO
Do chronotherapeutic formulations and long-acting antihypertensive agents improve 24-hour blood pressure control and attenuate the early morning blood pressure surge in hypertensive patients?
P
Population
Hypertensive patients and susceptible individuals at risk for cardiovascular events
I
Intervention
Chronotherapeutic formulations of drugs and intrinsically long-acting antihypertensive agents
O
Outcome
24-hour blood pressure control and attenuation of the early morning rise in blood pressuresurrogate
Chronotherapeutic and long-acting antihypertensive agents are recommended to provide 24-hour blood pressure control and mitigate the early morning surge in blood pressure, which is associated with increased cardiovascular risk.
Cite This Study
William B. White (2001) studied this question.