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May 1, 2001HypertensionOpen Access

Cardiovascular Mortality in Hypertensive Men According to Presence of Associated Risk Factors

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Why the study?

Does the presence of associated risk factors increase cardiovascular mortality in hypertensive men across different age groups?

Population

89,983 men who had a standard health checkup at the Centre d'Investigations Préventives et Cliniques between…

Comparison

Presence of associated risk factors in… vs Normotensive men without associated risk factors

Design

Cohort

Follow-up

mean 14 years

Authors

FTFrédérique ThomasPreventive CardiologyARA. RudnichiAgence Nationale de Sécurité Sanitaire de l’Alimentation, de l’Environnement et du TravailABAnne-Marie BacriCentre de Médecine Préventive

Discussion

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Overview

May support age-stratified risk assessment in hypertension; leaves open whether targeting comorbidities improves outcomes differently by age.

Structured PICO

Does the presence of associated risk factors increase cardiovascular mortality in hypertensive men across different age groups?

P
Population
89,983 men (29,640 normotensive without associated risk factors and 60,343 hypertensive with and without associated risk factors) who had a standard health checkup at the Centre d'Investigations Préventives et Cliniques between 1978 and 1988.
I
Intervention
Presence of associated risk factors (total cholesterol >=2.5 g/L, personal history of diabetes, current smoking, body mass index >28 kg/m2, and heart rate >80 bpm) in hypertensive men
C
Comparator
Normotensive men without associated risk factors (reference group)
O
Outcome
Cardiovascular disease (CVD) mortalityhard clinical

Associated risk factors significantly increase cardiovascular mortality in younger hypertensive men, whereas hypertension itself is the major determinant of risk in older men.

Cite This Study

Thomas et al. (2001) studied this question.

synapsesocial.com/papers/6a70463fac440176ef28ecd8https://doi.org/10.1161/01.hyp.37.5.1256

Topics

Hypertension management
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