December 1, 2013Circulation Cardiovascular InterventionsOpen Access

Impact of Transcatheter Pulmonary Valve Replacement on Biventricular Strain and Synchrony Assessed by Cardiac Magnetic Resonance Feature Tracking

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Why the study?

Does transcatheter pulmonary valve replacement improve biventricular strain and synchrony in patients with right ventricular outflow tract conduit dysfunction?

Population

31 patients with right ventricular outflow tract conduit dysfunction, including subgroups with predominant…

Comparison

Transcatheter pulmonary valve (TPV) replacement vs Pre-TPV replacement baseline

Design

Cohort

Authors

DHDavid M. HarrildPediatric Cardiology EMEdward MarcusBoston Children's Hospital BHBabar HasanSindh Institute of Urology and Transplantation

Discussion

Member takes

Implication

TPV replacement was associated with improved LV strain; hypothesis-generating for biventricular effects, needs randomized confirmation.

Structured PICO

Does transcatheter pulmonary valve replacement improve biventricular strain and synchrony in patients with right ventricular outflow tract conduit dysfunction?

Population

31 patients with right ventricular outflow tract conduit dysfunction (18 with tetralogy of Fallot), including subgroups with predominant pulmonary regurgitation (n=13) or stenosis (n=18), from a single center in the US Melody TPV trial.

Intervention

Transcatheter pulmonary valve (TPV) replacement

Comparator

Pre-TPV replacement baseline (intra-patient comparison)

Outcome

Biventricular strain and mechanical synchrony assessed by cardiac magnetic resonance feature trackingsurrogate

Transcatheter pulmonary valve replacement improves global left ventricular strain and right ventricular strain in patients with right ventricular outflow tract conduit dysfunction.

Cite This Study

Harrild et al. (2013) studied this question.

synapsesocial.com/papers/6a70469ca2d7cf2e39c2a4f0 https://doi.org/10.1161/circinterventions.113.000690

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Impact of Transcatheter Pulmonary Valve Replacement on Biventricular Strain and Synchrony Assessed by Cardiac Magnetic Resonance Feature Tracking

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Impact of Transcatheter Pulmonary Valve Replacement on Biventricular Strain and Synchrony Assessed by Cardiac Magnetic Resonance Feature Tracking

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider