Why the study?
Does surgical pulmonary valve replacement improve biventricular function and exercise capacity in patients with severe pulmonary regurgitation?
Population
73 patients with severe pulmonary regurgitation undergoing surgical pulmonary valve replacement.
Comparison
Surgical pulmonary valve replacement (PVR) vs Pre-surgery baseline
Design
Cohort
Follow-up
1-year post-surgery
Authors
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May increase LV output and improve NYHA class after PVR; leaves open effects on peak VO2.
Does surgical pulmonary valve replacement improve biventricular function and exercise capacity in patients with severe pulmonary regurgitation?
Surgical pulmonary valve replacement for severe pulmonary regurgitation improves right ventricular filling and left ventricular stroke volume, and diastolic ventricular function correlates with exercise capacity, though peak VO2 did not significantly change.
Frigiola et al. (2012) studied this question.
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