Why the study?
Does surgical pulmonary valve replacement improve left ventricular systolic function in patients with repaired tetralogy of Fallot or critical pulmonary stenosis?
Population
40 consecutive patients with repaired tetralogy of Fallot or critical pulmonary stenosis, age 29±9 years…
Comparison
Surgical pulmonary valve replacement (PVR) vs Pre-PVR baseline (intra-patient comparison)
Design
Cohort
Follow-up
midterm
Authors
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PVR was associated with modest LVEF gains, greatest in those with low pre-PVR values; leaves open clinical outcome impact and optimal timing.
Does surgical pulmonary valve replacement improve left ventricular systolic function in patients with repaired tetralogy of Fallot or critical pulmonary stenosis?
Surgical pulmonary valve replacement significantly improves left ventricular ejection fraction, particularly in patients with depressed pre-operative LV function.
Zaidi et al. (2018) studied this question.
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