Why the study?
Does pulmonary valve replacement improve right ventricular function in patients with repaired tetralogy of Fallot?
Population
25 consecutive patients with tetralogy of Fallot, 25.2 years +/- 7.0 after repair
Comparison
Pulmonary valve replacement (PVR) vs Pre-operative baseline (before PVR)
Design
Cohort
Follow-up
19 months
Authors
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May support PVR for RV remodeling in repaired TOF; hypothesis-generating and requires RCTs before practice change.
Does pulmonary valve replacement improve right ventricular function in patients with repaired tetralogy of Fallot?
Pulmonary valve replacement in patients with repaired tetralogy of Fallot leads to rapid and sustained improvement in right ventricular function, though recurrent pulmonary regurgitation blunts this recovery.
Straten et al. (2004) studied this question.
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