December 1, 2007Journal of Hypertension
Predictors of mortality in patients with type 2 diabetes with or without diabetic nephropathy: a follow-up study
Why the study?
Does a non-dipping or reversed pattern of night blood pressure predict all-cause mortality in patients with type 2 diabetes?
Population
104 patients with type 2 diabetes (51 with diabetic nephropathy and 53 with persistent normoalbuminuria)
Comparison
Non-dipping or reversed pattern of night blood… vs Normal dipping of night blood pressure
Design
Cohort
Follow-up
Mean 9.2 years (range 0.5-12.9)
Authors
Discussion
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Member takes
Implication
Reversed dipping may mark higher mortality risk in T2D; supports ambulatory monitoring for stratification but leaves open whether targeting it improves outcomes.
Structured PICO
Does a non-dipping or reversed pattern of night blood pressure predict all-cause mortality in patients with type 2 diabetes?
P
Population
104 patients with type 2 diabetes (51 with diabetic nephropathy and 53 with persistent normoalbuminuria)
I
Intervention
Non-dipping or reversed pattern of night blood pressure on 24-h ambulatory blood pressure monitoring
C
Comparator
Normal dipping of night blood pressure
O
Outcome
All-cause mortalityhard clinical
In patients with type 2 diabetes, a non-dipping or reversed nocturnal blood pressure pattern is an independent predictor of all-cause mortality, highlighting the prognostic value of 24-hour ambulatory blood pressure monitoring.
Cite This Study
Astrup et al. (2007) studied this question.