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August 1, 1974Circulation ResearchOpen Access

Autonomic Nervous System and Benign Essential Hypertension in Man

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Population

70 subjects (56 with benign essential hypertension)

Design

Cross-sectional

Authors

JCJ. L. CucheInsermOKOtto KuchelMedical Council of CanadaABAndré BarbeauAlberta Bible College

Discussion

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Implication

May reflect distinct pathophysiology across hypertension phenotypes; leaves open causal and prognostic roles pending longitudinal confirmation.

Structured PICO

P
Population
70 subjects (56 with benign essential hypertension)
C
Comparator
Normotensive subjects
O
Outcome
Levels of catecholamines, plasma renin activity, and urinary creatinine, sodium, and potassiumsurrogate

Benign essential hypertension represents a continuous spectrum of clinical and biochemical changes related to blood pressure levels, with distinct adrenergic profiles in labile versus stable forms.

Cite This Study

Cuche et al. (1974) studied this question.

synapsesocial.com/papers/6a7046a5f44fa9f079dddd91https://doi.org/10.1161/01.res.35.2.281
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Human Serum Dopamine-β-Hydroxylase: Relationship to Hypertension and Sympathetic Activity1973 · 121 citations
  2. 2Role of the Sympathetic Nervous System in Regulating Renin and Aldosterone Production in Man *1967 · 316 citations
  3. 3The Haemodynamic Consequences of Adaptive Structural Changes of the Resistance Vessels in Hypertension1971 · 269 citations
  4. 4Role of Parasympathetic Inhibition in the Hyperkinetic Type of Borderline Hypertension1971 · 337 citations
  5. 5Relationship between the Adrenergic Nervous System and Renin during Adaptation to Upright Posture: A Possible Role for 3,4-Dihydroxyphenethylamine (Dopamine)1972 · 104 citations