Why the study?
Does systematic ablation of the peripheral sympathetic nervous system alter blood pressure responses induced by spinal cord injury in cats?
Population
24 cats subjected to 400 gm-cm contusions of the thoracic cord
Comparison
Systematic ablation of the peripheral… vs Sham operation or no treatment
Design
Preclinical
Follow-up
3 or 24 hours after ablations
Authors
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No immediate clinical role for sympathetic ablation in SCI hypertension; leaves open dual thoracic-adrenal pathways for future mechanistic study.
Does systematic ablation of the peripheral sympathetic nervous system alter blood pressure responses induced by spinal cord injury in cats?
This preclinical study demonstrates that both thoracic sympathetic ganglia and adrenal glands mediate the hypertensive response to spinal cord injury.
Young et al. (1980) studied this question.
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