Population
Highly pure platelet preparations
Comparison
Transcriptomic analysis using Affymetrix… vs Other tissues and published proteomic data
Design
Preclinical
Authors
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Hypothesis-generating in animal models; leaves open human validation for transcriptomic prediction of platelet proteins.
Despite being anucleate, the platelet proteome is mirrored in its transcriptome, providing a novel approach to predict platelet proteins and understand platelet biology.
McRedmond et al. (2003) studied this question.
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