Why the study?
Does Major Depressive Disorder reduce heart rate variability in older primary care patients?
Population
272 older primary care patients, recruited in family practices in the Netherlands.
Comparison
Major Depressive Disorder (MDD) exposure vs Non-depressed controls matched for age and gender
Design
Cross-sectional
Authors
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MDD-linked HRV reduction may contribute to elevated cardiovascular risk in older adults; leaves open causal mechanisms and treatment effects.
Does Major Depressive Disorder reduce heart rate variability in older primary care patients?
Older primary care patients with major depressive disorder have significantly reduced heart rate variability, which may partially explain the increased cardiovascular risk in this population.
Kooy et al. (2006) studied this question.
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