Population
Dictyostelium discoideum cells
Comparison
Overexpression of RasGEF Q GEF domain or RasGEF… vs Wild-type cells
Design
Preclinical
Authors
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RasGEF Q-myosin findings in Dictyostelium remain hypothesis-generating; leaves open any role in mammalian cardiac cell dynamics.
RasGEF Q acts as an exchange factor for RasB in Dictyostelium, linking starvation signals to the regulation of myosin II-dependent processes.
Mondal et al. (2008) studied this question.
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