What question did this study set out to answer?

To evaluate the relative frequencies and molecular epidemiological characteristics of viral hepatitis types A through E among an Inuit population in West Greenland.

September 1, 1997Journal of Viral Hepatitis

Epidemiological study of viral hepatitis types A, B, C, D and E among Inuits in West Greenland

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Authors

BLBarbara LangerIo Therapeutics (United States)GFGert FrösnerTechnical University of Munich ABAlbrecht von BrunnDepartment of Virology

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Implication

Descriptive study reveals high exposure to hepatitis A and B in an Inuit population, indicating substantial endemic transmission alongside low rates of hepatitis C and E.

Key Points

To evaluate the relative frequencies and molecular epidemiological characteristics of viral hepatitis types A through E among an Inuit population in West Greenland.
Conducted a descriptive epidemiological survey analyzing serum samples from 503 Inuit participants (186 males, 317 females; mean age 35 years, range 7–79 years) in West Greenland.
Tested sera for serological markers across viral hepatitis types A through E, and performed polymerase chain reaction and genotyping on positive samples to assess viral DNA/RNA.
Hepatitis A prevalence averaged 54%, sharply increasing from 9% to 50% between the second and third decades of life.
Evidence of past or current HBV infection was found in 42% of participants, with 7% identified as HBsAg carriers; among carriers, 6% were HBeAg positive, 49% had detectable HBV DNA, and viral isolates were classified as genomic group D (83%, serotype ayw2) or group A (17%, serotype adw2).
Hepatitis D markers occurred in 7% of individuals with HBV helper markers and in 40% of HBsAg carriers, whereas anti-HCV was detected in <1% (0% HCV RNA positive) and anti-HEV was detected in 3% (0% HEV RNA positive).

Cite This Study

Langer et al. (1997) studied this question.

synapsesocial.com/papers/6a70506c439bab0cabc31c8f https://doi.org/10.1046/j.1365-2893.1997.00063.x

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Implication

Descriptive study reveals high exposure to hepatitis A and B in an Inuit population, indicating substantial endemic transmission alongside low rates of hepatitis C and E.

Epidemiological study of viral hepatitis types A, B, C, D and E among Inuits in West Greenland

Discussion

Member takes

Implication

Key Points

Cite This Study

Epidemiological study of viral hepatitis types A, B, C, D and E among Inuits in West Greenland

Discussion

Member takes

Implication

Key Points

Cite This Study

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