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July 29, 2011Catheterization and Cardiovascular Interventions

Transaortic transcatheter aortic valve implantation using edwards sapien valve

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Why the study?

Does transaortic TAVI provide similar 30-day mortality and procedural complication rates compared to transapical TAVI in patients with severe aortic stenosis unsuitable for transfemoral access?

Population

193 patients with severe aortic stenosis who underwent TAVI, of which 108 were unable to undergo…

Comparison

Transaortic Transcatheter Aortic Valve… vs Transapical (TA) TAVI

Design

Cohort

Follow-up

30 days

Authors

VBVinayak BapatMKMuhammed Zeeshan KhawajaRARizwan Attia

Discussion

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Overview

TAo-TAVI shows comparable 30-day mortality to TA-TAVI in this cohort; leaves open its role as alternative pending randomized data.

Structured PICO

Does transaortic TAVI provide similar 30-day mortality and procedural complication rates compared to transapical TAVI in patients with severe aortic stenosis unsuitable for transfemoral access?

P
Population
193 patients with severe aortic stenosis who underwent TAVI, of which 108 were unable to undergo transfemoral TAVI (17 accepted for transaortic TAVI and the remainder for transapical TAVI).
I
Intervention
Transaortic (TAo) Transcatheter Aortic Valve Implantation (TAVI) using the Edwards SAPIEN bioprosthesis via a partial upper sternotomy
C
Comparator
Transapical (TA) TAVI
O
Outcome
30-day mortality and procedural complicationshard clinical

Transaortic TAVI via partial sternotomy is a safe and feasible alternative to transapical TAVI for patients with severe aortic stenosis who are unsuitable for the transfemoral approach, particularly those with severe respiratory disease.

Cite This Study

Bapat et al. (2011) studied this question.

synapsesocial.com/papers/6a70518dfe4101aa97e01b6fhttps://doi.org/10.1002/ccd.23276
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Trans-apical aortic valve implantation: univariate and multivariate analyses of the early results from the SOURCE registry☆☆☆2010 · 87 citations
  2. 2Trans-catheter aortic valve implantation in the United Kingdom: NICE guidance2008 · 6 citations
  3. 3Percutaneous Transcatheter Implantation of an Aortic Valve Prosthesis for Calcific Aortic Stenosis2002 · 3,196 citations
  4. 4A prospective survey of patients with valvular heart disease in Europe: The Euro Heart Survey on Valvular Heart Disease2003 · 3,559 citations
  5. 5Prognostic value of chronic obstructive pulmonary disease in coronary artery bypass grafting☆2005 · 101 citations