Why the study?
To demonstrate the relationship between blood volume, cardiac size, cardiac output, and VO2max, and to quantify blood volume shifts during exercise and their impact on oxygen transport.
Comparison
Incremental cycle ergometer testing with blood volume, cardiac, and oxygen transport measurements
Design
Physiological study
Authors
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Larger resting blood volume was associated with higher maximal cardiac output; leaves open whether volume expansion augments VO2max in athletes.
Exercise induces a significant decrease in blood volume, but simultaneous hemoconcentration maintains arterial oxygen content and compensates for potential loss in maximum cardiac output.
Schierbauer et al. (2021) studied this question.
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