Why the study?
Many blood pressure clinical trials exclude advanced CKD and the elderly, leaving questions about whether lowering blood pressure improves prognosis and making target blood pressure difficult to define.
What are the optimal blood pressure targets and treatment strategies in elderly patients with chronic kidney disease?
What are the optimal blood pressure targets and treatment strategies in elderly patients with chronic kidney disease?
This review summarizes current guidelines for blood pressure control in elderly CKD patients, highlighting the lack of evidence and need for randomized trials in this vulnerable population.
May warrant cautious BP lowering in elderly CKD; leaves open whether it improves prognosis.
In elderly chronic kidney disease (CKD) patients, isolated systolic hypertension is common, the rate of renal function decline is slow, and there is a high possibility of physical damage due to side effects such as drug use-related orthostatic hypotension. Therefore, there are still many questions about whether lowering blood pressure in elderly patients will actually improve prognosis. Since many blood pressure-related clinical studies exclude advanced CKD and the elderly, it is particularly difficult to define target blood pressure in these populations. A randomized controlled trial is needed to establish optimal blood pressure targets and treatment strategies in elderly patients with CKD. This review seeks to summarize the guidelines available at this time.
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Jae Won Yang (2022) studied this question.
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