Why the study?
Left ventricular dysfunction in diabetic patients with CAD has been investigated by speckle-tracking echocardiography, but left atrial function in these patients has not been evaluated with this technique.
Does speckle-tracking echocardiography detect impaired left atrial function in diabetic patients with coronary artery disease compared to healthy controls?
Does speckle-tracking echocardiography detect impaired left atrial function in diabetic patients with coronary artery disease compared to healthy controls?
Speckle-tracking echocardiography reveals significant impairment in left atrial strain parameters in diabetic patients with coronary artery disease, even in the presence of normal left ventricular function.
STE of LA function in diabetic CAD patients is feasible but hypothesis-generating; leaves open its prognostic utility and impact on management.
Background: Diabetes mellitus (DM) and coronary artery disease (CAD) have intimate relationship, which is the most common reason of morbidity and death in diabetic participants. Left ventricular (LV) dysfunction in diabetic participants with CAD was investigated by speckle-tracking echocardiography (STE). However, LA function in participants with CAD has not been evaluated with this technique. Objective: To assess left atrial (LA) functions by STE in diabetic patients with coronary artery disease (CAD). Methods: In 50 participants with CAD, two-dimensional strain echocardiographic imaging was done to asses LA function. A control group of twenty healthy people was included. The procedure included both conventional echocardiography and STE. Peak atrial contraction strain (PACS) and peak atrial longitudinal strain (PALS) were measured as strain parameters. Results: PALS and PACS strain were significantly decreased among patient group than control group (18.46±6.41 versus 52.07±7.8%, P < 0.001 and 9.92±7.74 versus 20.03±1.35%, P < 0.001 respectively). Conclusion: LA strain Parameters is impaired in diabetic patients in comparison with control in spite of normal LV function.
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Elnoamany et al. (2022) studied this question.
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