Key result
Leukoaraiosis was associated with significantly greater middle cerebral artery pulsatility compared to patients without leukoaraiosis (0.91 vs 0.73, P<0.0001).
Population
100 patients recruited from the Oxford Vascular Study within 6 weeks of a transient ischemic attack or minor…
Design
Cross-sectional, MRI categorized by 2 independent observers
Authors
Loading...
May link large-artery stiffness to small-vessel disease after TIA; leaves open whether pulsatility reduction alters outcomes.
Observational (n=100)
No
Absolute Event Rate: 0.91% vs 0.73%
p-value: p=<0.0001
Middle cerebral artery pulsatility is strongly associated with leukoaraiosis in patients with recent TIA or minor stroke, suggesting large artery stiffening transmits pulsatility to cerebral small vessels.
Webb et al. (2012) conducted an observational in Recent transient ischemic attack or minor stroke (n=100). Leukoaraiosis vs. No leukoaraiosis was evaluated on Middle cerebral artery pulsatility (MCA-PI) (p=<0.0001). Leukoaraiosis was associated with significantly greater middle cerebral artery pulsatility compared to patients without leukoaraiosis (0.91 vs 0.73, P<0.0001).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: