MDCT Imaging of Non-Traumatic Thoracic Aortic Emergencies and Its Impact on Diagnosis and Management—A Reappraisal

Figure 1. Computed tomography angiography (CTA) provides a rapid noninvasive diagnosis of the entire aorta including aberrant anatomy and pathology. (A) A 74-year-old man presenting in ED with 10 h of abrupt onset of acute chest pain, improving anemia, hypotension (blood pressure of 70/40 mm Hg in both upper extremities), and shortness of breath. CTA shows a right aortic arch and a pleural and extrapleural left hematoma from an aneurysm (asterisk) of a retroesophageal aberrant left subclavian artery (ALSA). (B) More caudal axial scan shows the ALSA aneurysm rupture site (arrow). Note the anomalous course of the left brachiocefalic vein posterior to the ascending aorta. (C) CTA-delayed phase shows contrast medium extravasation in the extrapleural hematoma (asterisk); note extrapleural fat sign (arrow). (D) 3D volume rendering oblique sagittal reformat image clearly shows the aneurysm (asterisk) coming immediately off the ALSA origin (arrow) from a Kommerell’s diverticulum (arrowhead).

Figure 2. Usefulness of CTA low-dose unenhanced phase in acute aortic syndrome. (A) Noncontrast CT axial scan shows dissection flap (arrow) and displaced intimal calcifications (arrowhead) in supra-aortic vessels extension of type A aortic dissection in a 79-year-old-man with acute neck and back pain. (B) Axial image from noncontrast CT shows a crescent-shaped high-density rind in the ascending aorta, a typical appearance of type A acute intramural hematoma (arrowheads). (C) Noncontrast CT axial scan shows a large bilateral pleural effusion with increased density in the dependent aspect of the collection (hematocrit sign), highly suggestive of hemothorax (asterisk) from rupture of the descending thoracic aorta aneurysm. (D) Axial image of aorta from noncontrast CT shows hemomediastinum tracking along the main and right pulmonary arteries and hyperattenuating dissection flap (arrowheads) in ascending aorta in a 68-year-old woman with ruptured type A dissection.

Figure 3. (A) Coronal MPR image of CTA in a 57-year-old man with chest pain and troponin negative shows coexistence of an acute intramural hematoma in the ascending aorta (type A IMH, arrowheads) and a dual-barrel dissection in the abdominal aorta (arrows). (B,C) Axial CTA images in another patient, showing the extension of the dissection flap from the proximal arch (arrow) to its distal segment (arrowheads) after only 19 s in the same CTA examination. Aortic dissection may be a very dynamic process.

Figure 4. Pretest clinical probability assessment according to Aortic Dissection Detection Risk Score (ADD-RS) and D-Dimer (DD). ADD-RS score is based on 12 risk factors organized in three categories (0, low risk; 1, intermediate risk; 2–3. high risk). BP = blood pressure. * Caution in patients with early presentation (≤2 h) or long-lasting symptoms (≥1 week) [28].

Figure 5. CTA findings in aortic dissection. (A) Axial CTA image showing intimomedial rupture sign in the ascending aorta (arrow) in type A dissection, indicating direction of the intimomedial entrance tear from true to false lumen. (B) Coronal CTA MPR image showing the intimomedial flap travelling parallel to the aorta long axis. Note the cobweb sign by thin, string-like filaments of the media layer in the false lumen (arrowheads). (C) Axial CTA image shows pressure competition between lumina and opacified true lumen collapse (arrow). (D) The different density of the TL (more intensely opacified due to faster flow) and FL in the early angiographic phase allows them to be clearly distinguished in the coronal VR reconstruction.

Figure 6. CTA findings in classic dual-barrel aortic dissection. (A) Axial CTA images showing the “beak sign” (arrowheads) in the false lumen because its wall and intimomedial flap usually form acute angles resembling a bird’s beak. In the radiological report, maximum aortic diameter and minimum and maximum aortic true lumen diameter should be included. (B) Sagittal oblique MPR image of non-A-non-B dissection with descending-entry and retrograde arch extension (arrow) in a 75-year-old male presenting with acute chest pain. (C) Axial CTA images. Static aortic dissection is seen as protrusion of the intimal flap (arrow) into the ostium of the affected branch vessel causing subsequent partial or total thrombosis of the branch vessel with resulting perfusion impairments. Note left kidney partial infarct (arrowheads). (D) CTA oblique coronal VR reconstruction image shows a three lumina aortic dissection.

Figure 7. (A) Axial CTA image demonstrates thickening of the main pulmonary arterial wall (arrowheads) indicating IMH of the PA in ruptured Type A AD. (B) Axial CTA image shows entry tear (arrow) in the arch convexity in a 53-year-old man with severe chest pain. (C) 3D-VR parasagittal reconstruction image shows localized 4-vessels arch dissection (arrow) without supra-aortic trunks involvement. (D) 3D-VR parasagittal reconstruction image shows a non-A-non-B dissection with arch-entry and anterograde descending aorta involvement.

Figure 8. CT features of acute type B IMH in a 62-year-old man with abrupt chest pain and Type B IMH at baseline CTA examination. (A) Axial low-dose unenhanced CT image shows hyperdense crescent sign of the aortic wall (arrow). (B) Axial arterial phase CTA image in the same patient shows decreased diameter of the aortic lumen and the smooth luminal-wall interface. (C) Sagittal reconstruction CTA image shows decreased diameter of the aortic lumen (arrow) and a relative constant circumferential relationship with the wall.

Figure 9. Unstable Type A IMH complicated by ulcer-like projection (ULP). (A) Coronal oblique CTA shows type A IMH (arrowheads) in a 68-year-old man with hypertension and chest pain. The total aortic diameter was less than 50 mm and the IMH thickness less than 11 mm; he underwent medical management initially. (B) Three-day follow-up coronal oblique CTA image shows disease progression by an ULP due to opening of intimal tear (arrow). (C) 3D-volume-rendered (VR) reconstruction confirms ULP (arrow).

Figure 10. CTA features of Svensson’s Class 4 (PAU) and Class 3 (limited intimal tear) variants. (A) Axial unenhanced CT image shows aortic arch high-density intramural hematoma (IMH) in a 74-year-old male with acute neck and chest pain (arrowheads). (B) CTA axial scan in the same patient shows a flat penetrating ulcer (arrow) with associated IMH in the arch convexity. (C) CTA axial image shows a linear filling defect with subtle undermined edges (arrow) and eccentric medial one-sided bulge of the ascending aorta (arrowhead) without a clear intimomeadial flap or false lumen in a 58-year-old male with sudden onset of chest and back pain. (D) 3D-VR oblique coronal reconstruction confirms the eccentric one-sided saccular aortic bulging (‘‘mushroom cap’’ morphology) of class 3 dissection (arrow).

Figure 11. CTA of thoracic aorta aneurysms. (A) Marfan syndrome, a multisystem connective tissue disease caused by a defect in the protein fibrillin 1, and annuloaortic ectasia in a 42-year-old man. Sagittal MIP reconstruction image shows a proximal dilatation of the aortic anulus (1), sinuses of Valsalva (2) along with effacement of the STJ (4) producing a pear-shaped ascending aorta (3). (B) Axial CTA image shows sinuses ectasia in the same patient. In Marfan syndrome, a cut-off value of 5 cm of the ascending aorta diameter is recommended for surgical repair. (C) Axial CTA image shows a 12 cm ascending aorta aneurysm (asterisk) and a large mediastinal effusion. The risk of rupture of TAAs increases with size of the aneurysm according to Laplace’s law. (D) Axial CTA image shows a ruptured atherosclerotic aneurysm of the descending thoracic aorta. Note the high-attenuation fluid in the right pleural space, representing acute hemothorax (asterisk), and contrast medium extravasation from the aortic lumen (arrow).

Figure 12. CTA findings in impending rupture of the thoracic aorta aneurysms. (A) Missing calcium sign (arrowhead). (B) Thrombus fissuration (arrow). (C) Hyperattenuating crescent sign, periaortic stranding sign, and contour irregularity of the aneurysm. (D) Periaortic fat stranding blurs a focal area of the mediastinum and extends to the chest wall representing an inflammatory process (arrowheads) [111].