Underutilization of Evidence-Based Medications in Acute ST Elevation Myocardial Infarction
Why the study?
Does reperfusion therapy improve in-hospital mortality in patients presenting with acute STEMI compared to no reperfusion therapy?
Population
840 consecutive patients with acute myocardial infarction presenting with ST segment elevation at 20…
Comparison
Reperfusion therapy vs No reperfusion therapy
Design
Cohort
Follow-up
In-hospital
Authors
Discussion
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Member takes
Implication
Reperfusion was associated with lower STEMI mortality; leaves open impact of underutilization and delays on real-world outcomes.
Structured PICO
Does reperfusion therapy improve in-hospital mortality in patients presenting with acute STEMI compared to no reperfusion therapy?
P
Population
840 consecutive patients with acute myocardial infarction presenting with ST segment elevation (STEMI) at 20 hospitals in the United States and Canada between February and September 1994.
I
Intervention
Reperfusion therapy (thrombolytic therapy or primary percutaneous coronary intervention)
C
Comparator
No reperfusion therapy
O
Outcome
In-hospital mortalityhard clinical
Reperfusion therapy for STEMI was significantly underutilized and frequently delayed, despite being associated with markedly lower in-hospital mortality compared to no reperfusion.
Cite This Study
Cannon et al. (2002) studied this question.