Key result
Acute rheumatic fever with clinical or subclinical carditis was associated with significantly thicker mitral valve leaflets and more frequent valvar abnormalities compared to healthy controls (p<0.001).
Why the study?
Does Doppler echocardiography detect valvar abnormalities in patients with acute rheumatic fever and subclinical carditis compared to healthy controls?
Population
31 patients with acute rheumatic fever diagnosed according to modified Jones criteria, and 20 healthy…
Comparison
Cross-sectional Doppler echocardiographic… vs Healthy controls
Design
Cross-sectional
Authors
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May support echocardiography for subclinical carditis detection in acute rheumatic fever; leaves open prospective validation before changing practice.
Cross-Sectional (n=51)
Does Doppler echocardiography detect valvar abnormalities in patients with acute rheumatic fever and subclinical carditis compared to healthy controls?
p-value: p=<0.001
Echocardiography is a sensitive method for detecting valvar abnormalities and diagnosing subclinical carditis in patients with acute rheumatic fever without apparent cardiac involvement.
Caldas et al. (2006) conducted a cross-sectional in Acute rheumatic fever (n=51). Acute rheumatic fever with clinical or subclinical carditis vs. Healthy controls was evaluated on Quantitative and qualitative findings of mitral and aortic valvar abnormalities (p=<0.001). Acute rheumatic fever with clinical or subclinical carditis was associated with significantly thicker mitral valve leaflets and more frequent valvar abnormalities compared to healthy controls (p<0.001).
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