Key result
Colour flow Doppler detects subclinical regurgitation in ~91% of acute rheumatic fever patients without clinical carditis.
Why the study?
The frequency of mitral and aortic valvar regurgitation in children with acute rheumatic fever without clinically evident carditis was not well defined.
Does colour flow Doppler imaging detect subclinical valvar heart disease in children with acute rheumatic fever without clinically evident carditis?
Population
18 children with acute rheumatic fever without clinical carditis and controls in Qatar
Comparison
Colour flow Doppler imaging vs non-rheumatic control subjects
Design
Non-randomised observational study
Follow-up
18 to 36 months for quiescent group
Authors
Loading...
Subclinical mitral/aortic regurgitation occurs in ARF without clinical carditis; leaves open whether Doppler findings warrant revised Jones criteria or screening.
Observational
No
Does colour flow Doppler imaging detect subclinical valvar heart disease in children with acute rheumatic fever without clinically evident carditis?
Absolute Event Rate: 90.9% vs 0%
Colour flow Doppler imaging can identify subclinical valvar disease in children with acute rheumatic fever who lack clinical signs of carditis, suggesting its value as an addition to diagnostic criteria.
Folger et al. (1992) conducted an observational in Acute rheumatic fever without evident carditis. Acute rheumatic fever without clinical carditis vs. Non-rheumatic control subjects was evaluated on Detection of mitral and aortic regurgitation. Colour flow Doppler imaging detected subclinical mitral or aortic regurgitation in 90.9% (10 of 11) of children with acute rheumatic fever without clinical carditis, compared to 0% in controls.
Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context: