Why the study?
Does intravenous adenosine alter atrial and ventricular repolarisation in patients undergoing diagnostic electrophysiology studies?
Population
19 patients undergoing routine diagnostic electrophysiology studies
Comparison
Intravenous adenosine 6 mg and 12 mg bolus doses vs Baseline (pre-adenosine administration)
Design
Other
Authors
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May warrant caution with adenosine in EP studies; leaves open arrhythmia risk implications.
Does intravenous adenosine alter atrial and ventricular repolarisation in patients undergoing diagnostic electrophysiology studies?
Intravenous adenosine dose-dependently shortens atrial but not ventricular action potential duration, an effect that is independent of beta-adrenergic blockade.
Nunain et al. (1992) studied this question.
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