Key result
Epicardial radiofrequency catheter ablation successfully eliminated abnormal electrograms, with no recurrence of ventricular arrhythmias or ICD shocks reported during a 12-month follow-up.
Why the study?
Brugada syndrome carries a significant risk of arrhythmic death, and managing associated ventricular arrhythmias remains particularly challenging.
Does epicardial radiofrequency catheter ablation prevent recurrent ventricular arrhythmias in a patient with Brugada syndrome and electrical storm?
Case Report (n=1)
No
Does epicardial radiofrequency catheter ablation prevent recurrent ventricular arrhythmias in a patient with Brugada syndrome and electrical storm?
Epicardial substrate ablation, aided by warm saline infusion to expose abnormal potentials, successfully prevented ventricular arrhythmia recurrence in a patient with Brugada syndrome and electrical storm.
May support epicardial ablation for refractory VA; leaves open confirmation in larger prospective studies.
Despite being a rare condition, Brugada syndrome (BrS) poses a significant risk of arrhythmic death, and managing associated ventricular arrhythmias is particularly challenging. Here, we present a case where percutaneous ablation targeted an arrhythmogenic substrate in a patient with BrS and recurrent ventricular fibrillation (VF). Epicardial mapping revealed abnormal potential areas in the right ventricle’s outflow tract and free wall. Injection of warmed saline into the pericardial space caused further delay in local electrograms and expanded the abnormal potential [...]
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Filho et al. (2024) conducted a case report in Brugada syndrome with electrical storm (n=1). Epicardial radiofrequency catheter ablation was evaluated on Recurrence of ventricular arrhythmias, ICD shocks, or syncope. Epicardial radiofrequency catheter ablation successfully eliminated abnormal electrograms, with no recurrence of ventricular arrhythmias or ICD shocks reported during a 12-month follow-up.
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