Key result
Single-cell technologies have emerged as powerful approaches to analyze Foot-and-Mouth Disease Virus infection at the resolution of individual cells, revealing cellular heterogeneity.
Why the study?
Foot-and-mouth disease virus causes acute and persistent infections affecting animal husbandry, and emerging single-cell techniques provide powerful approaches to explore viral infection mechanisms and host-virus interactions at the individual cell level.
Single-cell technologies provide high-resolution insights into the heterogeneity of FMDV infections and host-virus interactions.
With the rapid development of single-cell technologies, the mechanisms underlying viral infections and the interactions between hosts and viruses are starting to be explored at the single-cell level. The foot-and-mouth-disease (FMD) virus (FMDV) causes an acute and persistent infection that can result in the break-out of FMD, which can have serious effects on animal husbandry. Single-cell techniques have emerged as powerful approaches to analyze virus infection at the resolution of individual cells. In this review, the existing single-cell studies examining FMDV will be systematically summarized, and the central themes of these studies will be presented.
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Wang et al. (2020) conducted a review in Foot-and-Mouth Disease Virus (FMDV) infection. Single-cell analysis technologies was evaluated. Single-cell technologies have emerged as powerful approaches to analyze Foot-and-Mouth Disease Virus infection at the resolution of individual cells, revealing cellular heterogeneity.
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