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December 1, 2021Journal of Cardiovascular EmergenciesOpen Access

Patients with right ventricular outflow tract tachycardia had significantly higher epicardial adipose tissue thickness compared to healthy controls (0.914 cm vs 0.488 cm, p <0.001).

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Why the study?

Epicardial adipose tissue (EAT) may contribute to idiopathic RVOT tachycardia pathophysiology through inflammatory or autonomic mechanisms, but the relationship between EAT thickness and RVOT tachycardia required investigation.

Population

55 patients with RVOT tachycardia and 60 control subjects

Comparison

Patients with RVOT tachycardia vs control subjects

Key result

Patients with right ventricular outflow tract tachycardia had significantly higher epicardial adipose tissue thickness compared to healthy controls (0.914 cm vs 0.488 cm, p <0.001).

Authors

FKFerdi KahramanGebze Technical UniversitySKSelçuk KanatSan Diego Cardiac CenterTPTezcan PekerBursa Technical University

Discussion

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Overview

Suggests possible link in RVOT tachycardia; hypothesis-generating and requires prospective validation before clinical use.

Study Design

Type

Cross-Sectional (n=115)

Multicenter

No

Structured PICO

P
Population
115 adults (mean age 39 years, 39% female), comprising 55 patients with right ventricular outflow tract tachycardia and 60 healthy controls, evaluated cross-sectionally.
O
Outcome
Epicardial adipose tissue (EAT) thickness measured by transthoracic echocardiographysurrogate

Main Result

Absolute Event Rate: 0.914% vs 0.488%

p-value: p=<0.001

Increased epicardial adipose tissue thickness is associated with the presence of idiopathic right ventricular outflow tract tachycardia, suggesting a potential mechanical, metabolic, or autonomic pathophysiological link.

Limitations

  • Did not evaluate plasma inflammatory markers and inflammatory activity of the EAT
  • Could not detect the locations of cardiac ganglionated plexuses
  • Used 2D echocardiography for the evaluation of EAT thickness instead of cardiac magnetic resonance imaging or cardiac computed tomography

Cite This Study

Kahraman et al. (2021) conducted a cross-sectional in Right Ventricular Outflow Tract (RVOT) tachycardia (n=115). Right Ventricular Outflow Tract (RVOT) tachycardia vs. Healthy controls was evaluated on Epicardial adipose tissue (EAT) thickness (p=<0.001). Patients with right ventricular outflow tract tachycardia had significantly higher epicardial adipose tissue thickness compared to healthy controls (0.914 cm vs 0.488 cm, p <0.001).

synapsesocial.com/papers/6a7065fa35aa2c282ce1b641https://doi.org/10.2478/jce-2021-0019
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