Paranasal Sinuses In Cystic Fibrosis

Since Andersen's¹original description of cystic fibrosis (CF) of the pancreas, its various manifestations have been widely studied.²⁻¹⁷Recognition of and interest in the various clinical expressions of CF have resulted from such factors as (a) the increasing longevity of patients with more successful management, (b) heightened medical awareness of the disease, and (c) the availability of more sensitive diagnostic tests permitting the identification of mild or unusual cases. We have been impressed by the high incidence of abnormal roentgenograms of the sinuses in these individuals without symptoms of sinus disease. The purpose of this report is to present this observation and to discuss its significance. This observation has been mentioned only briefly by previous authors.¹⁸⁻²¹ Materials and Methods All pediatric cases of CF seen in the Children's Treatment Center of the National Jewish Hospital and in the Department of Pediatrics, University of Colorado Medical Center were