Why the study?
Does combination chemotherapy with adriamycin and cis-diamminedichloroplatinum improve tumor regression in patients with advanced solid tumors?
Population
48 patients with a variety of advanced solid tumors
Design
Case_series
Follow-up
1 to 18 months (median 6 months for responses)
Authors
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May indicate activity in advanced solid tumors; hypothesis-generating and requires randomized confirmation.
Does combination chemotherapy with adriamycin and cis-diamminedichloroplatinum improve tumor regression in patients with advanced solid tumors?
Combination chemotherapy with adriamycin and cis-diamminedichloroplatinum demonstrated efficacy in inducing tumor regression in a subset of patients with advanced solid tumors without major potentiation of toxicity.
Vogl et al. (1976) studied this question.
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