Why the study?
Does combination chemotherapy with adriamycin and cyclophosphamide improve objective response in women with advanced breast cancer?
Population
55 consecutive women with advanced breast cancer, mean age 55 years (range 37-77), 20% aged 65 or older.
Design
Cohort
Follow-up
12 months
Authors
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May support this regimen in advanced breast cancer; leaves open need for randomized confirmation.
Does combination chemotherapy with adriamycin and cyclophosphamide improve objective response in women with advanced breast cancer?
Combination chemotherapy with adriamycin and cyclophosphamide is safe and effective for outpatient treatment of advanced breast cancer, achieving an 80% objective response rate.
Jones et al. (1975) studied this question.
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