Management of breast cancer patients failing adjuvant chemotherapy with adriamycin-containing regimens
Why the study?
What are the outcomes of various treatment modalities in breast cancer patients failing adjuvant chemotherapy with adriamycin-containing regimens?
Population
62 patients with breast cancer treated with Adriamycin-containing adjuvant chemotherapy who developed…
Design
Cohort
Authors
Discussion
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Member takes
Implication
Supports salvage therapy after adriamycin failure; leaves open optimal modern regimens pending randomized data.
Structured PICO
What are the outcomes of various treatment modalities in breast cancer patients failing adjuvant chemotherapy with adriamycin-containing regimens?
P
Population
62 patients with breast cancer treated with Adriamycin-containing adjuvant chemotherapy who developed recurrent disease
I
Intervention
Various treatment modalities including chemotherapy (e.g., higher dose 5-fluorouracil, Adriamycin, and cyclophosphamide) and endocrine therapy
O
Outcome
Objective remission and survival from first relapsehard clinical
Patients with breast cancer relapsing after adriamycin-containing adjuvant chemotherapy can still achieve objective remission and prolonged survival with subsequent chemotherapy or hormonal therapy.
Cite This Study
Buzdar et al. (1981) studied this question.