Key result
Propofol-based total intravenous anesthesia and desflurane anesthesia resulted in similar extubation times (9.5 vs 9.8 minutes, p=0.39) and overall anesthesia-controlled times in patients undergoing open colorectal surgery.
Why the study?
Does propofol-based TIVA compared to desflurane anesthesia reduce anesthesia-controlled time and prolonged extubation in patients undergoing open colorectal surgery?
Cohort (n=395)
No
Does propofol-based TIVA compared to desflurane anesthesia reduce anesthesia-controlled time and prolonged extubation in patients undergoing open colorectal surgery?
Absolute Event Rate: 9.5% vs 9.8%
p-value: p=0.39
Propofol-based TIVA and desflurane anesthesia result in similar anesthesia-controlled times and rates of prolonged extubation in open colorectal surgery, with prolonged surgical time being the primary driver of delayed extubation.
Does not support preferring one agent for recovery metrics; leaves open need for randomized confirmation in colorectal surgery.
We conducted a retrospective study to investigate the anesthesia-controlled time and factors that contribute to prolonged extubation in open colorectal surgery. Using our hospital database, demographic data, various time intervals (waiting for anesthesia time, anesthesia time, surgical time, emergence time, exit from operating room after extubation, total operating room time, and post-anesthesia care unit stay time), and incidence of prolonged extubation (≥ 15 mins), were compared between patients who received desflurane/fentanyl-based anesthesia and total intravenous anesthesia via target-controlled infusion with fentanyl/propofol. Logistic regression analyses were performed to assess the association between variables that contributed to prolonged extubation. In conclusion, the anesthesia-controlled time was similar in desflurane anesthesia and propofol-based total intravenous anesthesia for open colorectal surgery in our hospital. Surgical time greater than 210 minutes, as well as age, contributed to prolonged extubation.
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Chan et al. (2016) conducted a cohort in Open colorectal surgery (n=395). Propofol-based total intravenous anesthesia (TIVA) vs. Desflurane anesthesia (DES) was evaluated on Extubation time (minutes) (p=0.39). Propofol-based total intravenous anesthesia and desflurane anesthesia resulted in similar extubation times (9.5 vs 9.8 minutes, p=0.39) and overall anesthesia-controlled times in patients undergoing open colorectal surgery.
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