Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
June 1, 2001Anesthesia & Analgesia

Multimodal Perioperative Management—Combining Thoracic Epidural Analgesia, Forced Mobilization, and Oral Nutrition—Reduces Hormonal and Metabolic Stress and Improves Convalescence After Major Urologic Surgery

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Does a multimodal perioperative management approach reduce hormonal and metabolic stress and improve recovery in patients undergoing radical cystectomy compared to traditional management?

Population

45 patients undergoing radical cystectomy

Comparison

Multimodal approach consisting of intraoperative… vs General anesthesia alone or general anesthesia…

Design

Cohort, Random allocation for the first 30 patients; Group 3 was treated in a…

Follow-up

up to the fifth postoperative day

Authors

GBG. BrodnerFachklinik HornheideHAHugo Van AkenUniversidad MayorLHL. HertleNational Institutes of Health

Discussion

Loading...

Member takes

Implication

May support multimodal care to ease stress and aid recovery after cystectomy; hypothesis-generating and needs RCT confirmation.

Structured PICO

Does a multimodal perioperative management approach reduce hormonal and metabolic stress and improve recovery in patients undergoing radical cystectomy compared to traditional management?

P
Population
45 patients undergoing radical cystectomy
I
Intervention
Multimodal approach consisting of intraoperative general anesthesia and thoracic epidural analgesia (TEA), postoperative patient-controlled TEA, early oral nutrition, and enforced mobilization (n=15)
C
Comparator
General anesthesia alone (n=15) or general anesthesia with intraoperative TEA (n=15), both followed by parenteral nutrition for 5 days after surgery
O
Outcome
Plasma and urine catecholamines, plasma cortisol, nitrogen balance, postoperative inflammatory nutrition index, pain relief, fatigue, sleep, overnight recovery, recovery of bowel function, and mobilization up to the fifth postoperative daysurrogate

A multimodal perioperative approach combining epidural analgesia, early oral nutrition, and forced mobilization reduces metabolic stress and improves clinical recovery after major urologic surgery.

Cite This Study

Brodner et al. (2001) studied this question.

synapsesocial.com/papers/6a706b14439bab0cabc327d2https://doi.org/10.1097/00000539-200106000-00049
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Overnight Hospitalization After Radical Prostatectomy1998 · 11 citations
  2. 2Workshop on How to Perform Clinical Outcome Studies1997 · 7 citations
  3. 3Overnight Hospitalization After Radical Prostatectomy1998 · 28 citations