Key result
Higher whole blood viscosity at low shear rate was significantly associated with an increased risk of silent cerebral infarction (OR 2.025; 95% CI 1.750-2.343; P < 0.001).
Why the study?
Is increased whole blood viscosity associated with silent cerebral infarction in subjects undergoing medical check-up?
Population
1487 subjects (868 men and 619 women) undergoing medical check-up
Comparison
Whole blood viscosity (WBV) levels vs Lower whole blood viscosity levels
Design
Cross-sectional
Authors
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Elevated low-shear viscosity may flag higher silent infarction risk; hypothesis-generating and should not yet change practice.
Cross-Sectional (n=1,487)
Is increased whole blood viscosity associated with silent cerebral infarction in subjects undergoing medical check-up?
Odds Ratio: 2.025 (95% CI 1.75–2.343)
p-value: p=< 0.001
Whole blood viscosity at low shear rate is independently associated with silent cerebral infarction, suggesting its potential utility as a risk marker for stroke.
Li et al. (2015) conducted a cross-sectional in Silent cerebral infarction (n=1,487). Whole blood viscosity vs. Lower whole blood viscosity was evaluated on Silent cerebral infarction (OR 2.025, 95% CI 1.750-2.343, p=< 0.001). Higher whole blood viscosity at low shear rate was significantly associated with an increased risk of silent cerebral infarction (OR 2.025; 95% CI 1.750-2.343; P < 0.001).
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