Key result
Reversal of warfarin anticoagulation and surgical evacuation successfully managed a subdural hematoma in a pregnant woman with double mechanical valves, leading to maternal recovery and a healthy newborn.
Why the study?
Managing warfarin-associated major haemorrhage in prosthetic valve disease is difficult, especially during pregnancy with its high thrombotic propensity, and such cases are very rare in the literature.
Population
One 35-year-old pregnant woman at 26 weeks with prosthetic aortic and mitral valves presenting with intracranial haemorrhage
Design
Case presentation
Authors
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May guide individualized decisions in rare high-risk pregnancies; leaves open the need for systematic data on peripartum anticoagulation.
Case Report (n=1)
Reversal of warfarin anticoagulation and multidisciplinary management, including surgical evacuation and careful bridging therapy, can lead to successful maternal and fetal outcomes in pregnant women with mechanical valves who develop major intracranial hemorrhage.
Oğuz et al. (2020) conducted a case report in Warfarin-associated intracranial haemorrhage in pregnancy with double mechanical valve replacement (n=1). Warfarin reversal and surgical evacuation was evaluated on Maternal and fetal survival/recovery. Reversal of warfarin anticoagulation and surgical evacuation successfully managed a subdural hematoma in a pregnant woman with double mechanical valves, leading to maternal recovery and a healthy newborn.
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