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January 1, 2018Case Reports in Obstetrics and GynecologyOpen Access

A Case of a Pregnant Woman with Thrombosis in an Artificial Aortic Valve Resulting in Severe Cerebral Hemorrhage in the Newborn

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Population

36-year-old pregnant woman with an artificial aortic valve who developed a thrombus in the aortic valve…

Design

Case_report

Follow-up

Up to delivery at 32 weeks of gestation

Authors

HKHidetake KameiHyogo UniversityYWYu WakimotoHyogo UniversityYMYumi MurakamiHyogo Medical University

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Implication

Urges caution with mid-pregnancy warfarin for mechanical valve thrombosis; leaves open optimal anticoagulation strategies in pregnant patients.

Structured PICO

P
Population
36-year-old pregnant woman with an artificial aortic valve (replaced at age 11) who developed a thrombus in the aortic valve during pregnancy.
I
Intervention
Warfarin administration re-started during mid-pregnancy (after week 22) for artificial valve thrombosis.
O
Outcome
Fetal cerebral hemorrhage and maternal thrombosis management.safety

Warfarin administration during pregnancy for artificial valve thrombosis carries a high risk of severe fetal cerebral hemorrhage, highlighting the complex and high-risk nature of anticoagulation management in pregnant patients with mechanical valves.

Cite This Study

Kamei et al. (2018) studied this question.

synapsesocial.com/papers/6a825f56004fcf503374ae6ehttps://doi.org/10.1155/2018/6154382
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Warfarin-Associated Fetal Intracranial Hemorrhage in Woman with Mitral Valve Replacements: A Case Report2009 · 20 citations
  2. 2Heparin Therapy During Pregnancy1989 · 204 citations
  3. 3Outcome of pregnancy in women with valve prostheses.1994 · 308 citations
  4. 4Hazards of Oral Anticoagulants During Pregnancy1980 · 172 citations
  5. 5Follow‐up study of children whose mothers were treated with warfarin during pregnancy1984 · 72 citations