Key result
Type 2 diabetes was associated with a higher total symptom distress score (8.4) compared to impaired (6.5) and normal glucose metabolism (6.1) (P=0.046).
Why the study?
Is worsening glucose metabolism and the presence of comorbidities associated with increased diabetes-related symptom distress?
Cross-Sectional (n=569)
Is worsening glucose metabolism and the presence of comorbidities associated with increased diabetes-related symptom distress?
Absolute Event Rate: 8.4% vs 6.1%
p-value: p=0.046
Worsening glucose metabolism is associated with increasing diabetes-related symptom distress, though this relationship is influenced by comorbidities such as ischemic heart disease and depression.
Higher symptom distress in type 2 diabetes may reflect comorbidities; leaves open causality and independent glucose effects.
OBJECTIVE: The purpose of this study was to determine the associations between diabetes-related symptom distress, glucose metabolism status, and comorbidities of type 2 diabetes. RESEARCH DESIGN AND METHODS: This was a cross-sectional sample of 281 individuals with normal glucose metabolism (NGM), 181 individuals with impaired glucose metabolism (IGM), and 107 subjects with type 2 diabetes. We used the revised type 2 Diabetes Symptom Checklist (DSC-R) to assess diabetes-related symptom distress. RESULTS: The total symptom distress score (range 0-100) was relatively low for diabetic subjects (mean +/- SD 8.4 +/- 9.4), although it was significantly different from that for subjects with IGM (6.5 +/- 7.1) and NGM (6.1 +/- 7.9) (F = 3.1, 2 d.f., P = 0.046). Ischemic heart disease was associated with elevated DSC-R scores on three subscales, whereas depression showed higher symptom distress levels across all DSC-R domains. CONCLUSIONS: Worsening glucose metabolism is associated with increasing diabetes-related symptom distress. This relationship is attenuated by ischemic heart disease and particularly by depression.
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Adriaanse et al. (2008) conducted a cross-sectional in Type 2 diabetes and impaired glucose metabolism (n=569). Worsening glucose metabolism (Type 2 diabetes and impaired glucose metabolism) vs. Normal glucose metabolism was evaluated on Total symptom distress score (DSC-R) (p=0.046). Type 2 diabetes was associated with a higher total symptom distress score (8.4) compared to impaired (6.5) and normal glucose metabolism (6.1) (P=0.046).
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