June 15, 2017Journal of Hypertension
Predictors of 5-year outcomes in malignant phase hypertension
Key result
White Caucasian (OR 12.02, 95% CI 1.64-88.15) and African-Caribbean (OR 15.55) ethnicities were associated with higher 5-year mortality compared to South Asians in malignant hypertension.
Population
351 patients with malignant hypertension whose 5-year survival status was known. Included 221 white…
Design
Cohort
Follow-up
5 years
Authors
Discussion
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Member takes
Implication
Ethnic disparities in malignant hypertension survival warrant monitoring; leaves open whether ethnicity-specific strategies improve outcomes.
Study Design
Type
Cohort (n=351)
Structured PICO
P
Population
351 patients with malignant hypertension and known 5-year survival status, followed for 5 years to identify predictors of poor outcomes.
O
Outcome
Composite endpoint of death or dialysis at 5-year follow-upcomposite
Main Result
Odds Ratio: 12.02 (95% CI 1.64–88.15)
p-value: p=0.01
Survival in malignant hypertension has improved significantly over recent decades, but abnormal renal function at presentation and non-South Asian ethnicity remain strong predictors of poor 5-year outcomes.
Cite This Study
Shantsila et al. (2017) conducted a cohort in Malignant phase hypertension (n=351). White Caucasian ethnicity vs. South Asian ethnicity was evaluated on Composite endpoint of death or dialysis (OR 12.02, 95% CI 1.64-88.15, p=0.01). White Caucasian (OR 12.02, 95% CI 1.64-88.15) and African-Caribbean (OR 15.55) ethnicities were associated with higher 5-year mortality compared to South Asians in malignant hypertension.