March 22, 2012Journal of Hypertension
Lack of impact of pulse pressure on outcomes in patients with malignant phase hypertension
Key result
Pulse pressure at presentation did not predict the risk of death or dialysis in patients with malignant phase hypertension over a median follow-up of 7 years.
Why the study?
Does pulse pressure at presentation predict death or dialysis in patients with malignant phase hypertension?
Population
365 patients with malignant phase hypertension from the West Birmingham MPH study, mean age 48, 66% male…
Design
Cohort
Follow-up
median 7 (IQR 1.5-14.8) years
Authors
Discussion
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Implication
Should not yet inform prognostic assessment in malignant hypertension; hypothesis-generating for alternative predictors like age and renal function.
Study Design
Type
Cohort (n=365)
Structured PICO
Does pulse pressure at presentation predict death or dialysis in patients with malignant phase hypertension?
P
Population
365 patients with malignant phase hypertension (mean age 48 years, 34% female) followed for a median of 7 years.
E
Exposure
Pulse pressure at presentation (divided into quartiles)
O
Outcome
Composite of death or dialysiscomposite
In patients with malignant phase hypertension, pulse pressure at presentation does not predict the risk of death or dialysis, whereas age, smoking, and renal function are independent predictors.
Cite This Study
Shantsila et al. (2012) conducted a cohort in malignant phase hypertension (MPH) (n=365). Pulse pressure was evaluated on death or dialysis. Pulse pressure at presentation did not predict the risk of death or dialysis in patients with malignant phase hypertension over a median follow-up of 7 years.