Key result
Patients aged 70 years or older undergoing colorectal cancer surgery had a significantly lower overall 5-year survival rate compared to younger patients (55% vs 75.2%, P=0.006), though disease-specific survival was similar.
Why the study?
Does age ≥ 70 years compared to < 70 years affect postoperative outcomes and survival in patients undergoing colorectal cancer surgery?
Population
403 patients operated on for colorectal cancer (CRC), mean age 67.2 years, 229 male and 174 female.
Comparison
Colorectal cancer surgery in patients aged ≥ 70… vs Colorectal cancer surgery in patients aged < 70…
Design
Cohort
Follow-up
5 years
Authors
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May support resection in selected elderly patients given similar disease-specific survival; leaves open comorbidity-focused strategies in prospective studies.
Observational (n=403)
No
Does age ≥ 70 years compared to < 70 years affect postoperative outcomes and survival in patients undergoing colorectal cancer surgery?
Absolute Event Rate: 55% vs 75.2%
p-value: p=0.006
While elderly patients (≥70 years) have higher postoperative mortality and lower overall survival after colorectal cancer surgery, their disease-specific survival is comparable to younger patients, supporting surgical resection in this population.
Pedrazzani et al. (2009) conducted an observational in Colorectal cancer (n=403). Age ≥ 70 years vs. Age < 70 years was evaluated on Overall 5-year survival rate (p=0.006). Patients aged 70 years or older undergoing colorectal cancer surgery had a significantly lower overall 5-year survival rate compared to younger patients (55% vs 75.2%, P=0.006), though disease-specific survival was similar.
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