Population
In vitro model using proteins isolated from pig platelets and rabbit skeletal muscle alpha-tropomyosin
Comparison
Pig platelet tropomyosin added to F-actin… vs F-actin in the absence of tropomyosin, and…
Design
Preclinical
Authors
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Conserved tropomyosin function across isoforms; extends actin regulation insights but leaves open human cardiovascular relevance.
Pig platelet tropomyosin functions similarly to skeletal muscle tropomyosin in protecting F-actin microfilaments from disassembly and cross-linking by other actin-binding proteins.
Prulière et al. (1986) studied this question.
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