Population
Muscle actin (in vitro biochemical model)
Comparison
Muscle tropomyosin vs Actin without tropomyosin
Design
Preclinical
Authors
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These kinetic shifts refine actin regulation models in sarcomeres; leaves open effects on cardiac contractility in vivo.
Tropomyosin alters the kinetics of actin polymerization by inhibiting association and dissociation rates without changing the critical concentration.
Lal et al. (1986) studied this question.
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