Increased QTc Dispersion Is Related to Blunted Circadian Blood Pressure Variation in Normoalbuminuric Type 1 Diabetic Patients
Population
106 normoalbuminuric normotensive type 1 diabetic patients on insulin only, with no antihypertensive or…
Design
Cross-sectional, ECG measurement made by one observer blinded to other data
Authors
Discussion
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Member takes
Implication
Should not yet change BP monitoring in diabetes; leaves open QTc dispersion as a marker of nocturnal nondipping.
Structured PICO
P
Population
106 normoalbuminuric (urinary albumin excretion <20 microg/min) normotensive type 1 diabetic patients on insulin only, with no antihypertensive or other medical treatment.
O
Outcome
Association between QTc dispersion and circadian blood pressure variation (night/day ratio) and autonomic function.surrogate
In normoalbuminuric type 1 diabetic patients, increased QTc dispersion is associated with a reduced nocturnal fall in blood pressure and altered sympathovagal balance.
Cite This Study
Poulsen et al. (2001) studied this question.