March 1, 2001Diabetic Medicine
Prolonged QTc interval predicts mortality in patients with Type 1 diabetes mellitus
Why the study?
Does a prolonged QTc interval predict all-cause and cardiovascular mortality in adult patients with Type 1 diabetes mellitus?
Population
697 adult patients with Type 1 diabetes mellitus and resting baseline electrocardiograms, including 360 males.
Comparison
Prolonged QTc interval (QTc max) and QT dispersion vs Normal or shorter QTc interval
Design
Cohort
Follow-up
10 years
Authors
Discussion
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Member takes
Implication
QTc max may aid mortality risk stratification in T1DM; leaves open prospective validation before clinical adoption.
Structured PICO
Does a prolonged QTc interval predict all-cause and cardiovascular mortality in adult patients with Type 1 diabetes mellitus?
P
Population
697 adult patients with Type 1 diabetes mellitus (duration of diabetes ≥ 5 years) and resting baseline electrocardiograms, including 360 males.
I
Intervention
Prolonged QTc interval (QTc max) and QT dispersion
C
Comparator
Normal or shorter QTc interval
O
Outcome
All-cause and cardiovascular mortalityhard clinical
Prolonged QTc interval is an independent predictor of all-cause mortality in patients with Type 1 diabetes mellitus, highlighting its potential utility in risk stratification.
Cite This Study
Rossing et al. (2001) studied this question.