Key result
Left atrial dilation (≥24.4 mm/m2) significantly increased the risk of atrial fibrillation or flutter (HR 7.03) in patients with arrhythmogenic right ventricular dysplasia.
Why the study?
Does the presence of atrial fibrillation/flutter predict inappropriate ICD shocks, heart transplantation, and cardiac death in patients with ARVD?
Population
90 patients diagnosed with definite or borderline arrhythmogenic right ventricular dysplasia according to…
Comparison
Development of atrial fibrillation or atrial… vs Patients without AF-AFl
Design
Cohort
Follow-up
median 5.8 years (interquartile range 2.0-10.4)
Authors
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Atrial size monitoring may refine AF risk stratification in ARVD; leaves open effects on ICD shocks or mortality.
Observational (n=90)
Yes
Does the presence of atrial fibrillation/flutter predict inappropriate ICD shocks, heart transplantation, and cardiac death in patients with ARVD?
Hazard Ratio: 7.03 (95% CI 2.43–20.34)
p-value: p=<0.001
In patients with ARVD, atrial fibrillation/flutter is common (20%) and is associated with increased risks of inappropriate ICD shocks, heart transplantation, and cardiac death, with reduced RV function and atrial dilation serving as predictors.
Saguner et al. (2014) conducted an observational in Arrhythmogenic Right Ventricular Dysplasia (n=90). Left atrial dilation (≥24.4 mm/m2) vs. Left atrial diameter <24.4 mm/m2 was evaluated on Time to first episode of atrial fibrillation or atrial flutter (AF-AFl) (HR 7.03, 95% CI 2.43-20.34, p=<0.001). Left atrial dilation (≥24.4 mm/m2) significantly increased the risk of atrial fibrillation or flutter (HR 7.03) in patients with arrhythmogenic right ventricular dysplasia.
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