Key result
Patients with metabolic syndrome and arterial hypertension 1 degree showed a high prevalence of target organ damage, including 30% with carotid atherosclerosis and 40% with left ventricular hypertrophy.
Why the study?
Is metabolic syndrome with grade 1 arterial hypertension associated with unrecognized target organ damage compared to healthy volunteers?
Cross-Sectional (n=80)
Is metabolic syndrome with grade 1 arterial hypertension associated with unrecognized target organ damage compared to healthy volunteers?
Patients with metabolic syndrome and grade 1 hypertension have a high prevalence of unrecognized target organ damage, including left ventricular hypertrophy and carotid atherosclerosis.
Aims: to study the target organ damage in patients with metabolic syndrome (MS) and arterial hypertension (AH) 1 degree. Design and methods. We included 20 healthy volunteers and 60 patients with MS, AH 1 degree and dyslipidemia. Office blood pressure, 24-hour ambulatory blood pressure monitoring, measurements of the endothelial vasoactive mediators, carotid ultrasonography and echocardiography had performed at baseline. Results. The majority of patients with MS and AH 1 degree had metabolic abnormalities; the levels of vasoactive mediators were higher in comparison with control group; 30% of patients had signs of atherosclerotic process in carotid arteries; 40% of patients had left ventricular hypertrophy. Conclusion: the results showed high prevalence of target organ damage in patients with MS and AH 1 degree.
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Blinova et al. (2016) conducted a cross-sectional in Metabolic syndrome and arterial hypertension 1 degree (n=80). Metabolic syndrome and arterial hypertension 1 degree vs. Healthy volunteers was evaluated on Target organ damage (atherosclerotic process in carotid arteries and left ventricular hypertrophy). Patients with metabolic syndrome and arterial hypertension 1 degree showed a high prevalence of target organ damage, including 30% with carotid atherosclerosis and 40% with left ventricular hypertrophy.
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